๐Ÿ”ฌ Bred Phage

A phage that has been subject to selection such as for modification in host range.

by Stephen T. Abedon Ph.D. (abedon.1@osu.edu)

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About this entry: Bred Phage is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1

phage.org/terms/bred_phage.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

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Bred Phage: A phage that has been subject to selection such as for modification in host range.

Discussion

<p>Breeding of phages is essentially equivalent to experimental class="bap-term">adaptation of phages to particular medical+condition" class="bap-term">conditions or hosts. This is a process that phagologists have been subjecting phages to almost since the discovery of phages, whether as a means of increasing phage virulence or related efforts to modify phage host range.

Phage breeding can involve wikipedia.org/wiki/Serial_passage" class="bap-term" target=_blank>serial passage of phages. Another example of this process is the selection for phages that resist elimination from blood as mediated by the mouse reticuloendothelial system (a.k.a., mononuclear phagocytic system).

For further consideration of phage breeding, especially from a more microbial population biology/evolutionary perspective, see Bull (2008).

External links

References

  • Bull (2008).

How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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Bred Phage — terms.phage.orgphage.org — Stephen T. Abedon — Version 2026.05.14