๐Ÿ”ฌ Efficiency of Plating (EOP)

Relative number of plaques that a phage stock is capable of producing.

by Stephen T. Abedon Ph.D. (abedon.1@osu.edu)

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About this entry: Efficiency of Plating is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1

phage.org/terms/efficiency_of_plating.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

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Efficiency of Plating: Relative number of plaques that a phage stock is capable of producing.

Discussion

<p>Note that efficiency of plating is not equivalent to phage viability on a given host or under a given set of medical+condition" class="bap-term">conditions, though it often is used as such. This non-equivalency is a consequence of the wikipedia.org/wiki/Complexity" target="_blank" class="bap-term">complexity of plaque formation, which requires not just phage ability to productively infect a given host (= viability) but also rate of phage population growth as well as physical virion spread within a bacterial lawn, and even rate and extent of bacterial lawn growth.

See efficiency of center of infection for further discussion of this non-equivalence of phage inviability and failure to form plaques. For additional discussion of this issue, see nih.gov/pubmed/19066821" target="_blank" class="bap-term">Abedon and Yin (2009).

This is the definition from Adams (1959), p. 439: "Plaque titer of a phage preparation, determined by plating under stated conditions, relative to some other estimate, usually higher, of the concentration of phage particles."

External links

References

How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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Efficiency of Plating — terms.phage.orgphage.org — Stephen T. Abedon — Version 2026.05.14