๐Ÿ”ฌ Immunity Region

Locaion on a temperate phage chromosome that is responsible for maintaining the lysogenic state and, as a consequence, effecting immunity against superinfecting phages.

by Stephen T. Abedon Ph.D. (abedon.1@osu.edu)

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About this entry: Immunity Region is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1

phage.org/terms/immunity_region.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

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Immunity Region: Locaion on a temperate phage chromosome that is responsible for maintaining the lysogenic state and, as a consequence, effecting immunity against superinfecting phages.

Discussion

<p>An enormous amount of detail is known of the phage λ immunity region with numerous reviews in existence. Relatively early in the process of characterizing the λ immunity region, by contrast, the glossary from Hershey (1971), p. 775, defined "immunity region" in this manner: "The segment of a temperate phage chromosome responsible for immunity. More specifically in λ, the regions called imm434 and imm21, consisting of λ DNA that cannot be crossed into a hybrid having the immunity of phage 434 or 21, respectively."

External links

References

  • Hershey (ed.) (1971). The Bacteriophage Lambda. Cold Spring Harbor Laboratory.

How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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Immunity Region — terms.phage.orgphage.org — Stephen T. Abedon — Version 2026.05.14