by Stephen T. Abedon Ph.D. Steve Abedon, Ph.D., has taught well over 100 individual classes and ~10 individual courses (including introductory biology, microbiology, physiology, biochemistry, etc.) over his 30+ years as a college professor. He has over 150 publications, including multiple monographs, and is ranked in the top 1 or 2 percent among researchers of all disciplines worldwide. His research focuses on bacteriophage biology and phage therapy. (abedon.1@osu.edu)
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phage.org/terms/monophage.html · Abedon’s Books · DOI: 10.5281/zenodo.20173633
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The concept of a monophage is used in contrast to that of phage cocktail, or polyphage. Note that in principle, contrasting one definition of polyphage, one might also use the term monophage to describe a phage virion into which only a single phage genome has been packaged.
The utility of use of a monophage formulation versus a cocktail is the ease of development for monophages. This, however, comes at a cost of versatility, specifically with monophages displaying the narrowest possible antibacterial spectrum of activity, though this breadth will vary depending on phage host range.
Abedon, S.T. (2026). Phage Terms. https://terms.phage.org · 10.5281/zenodo.20173633
Every term in the Glossary of Bacteriophage Terms. The current page is highlighted purple.