๐Ÿ”ฌ Monophage

A therapeutic formulation consisting of only a single phage type.

by Stephen T. Abedon Ph.D. (abedon.1@osu.edu)

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About this entry: Monophage is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1

phage.org/terms/monophage.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

How can I improve this page?  contact: terms@phage.org

Monophage: A therapeutic formulation consisting of only a single phage type.

Discussion

<p>The utility of use of a monophage formulation versus a cocktail is the ease of development for monophages. This, however, comes at a cost of versatility, specifically with monophages displaying the narrowest possible antibacterial spectrum of activity, though this breadth will vary depending on phage host range.

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How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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Monophage — terms.phage.org — phage.org — Stephen T. Abedon — Version 2026.05.14