๐Ÿ”ฌ Adsorption

The sum of processes culminating in attachment of a phage to a bacterium (and possibly including phage nucleic acid translocation, uptake, into a bacterium's cytoplasm as well).

by Stephen T. Abedon Ph.D. (abedon.1@osu.edu)

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About this entry: Adsorption is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1

phage.org/terms/adsorption.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

How can I improve this page?  contact: terms@phage.org

Adsorption: The sum of processes culminating in attachment of a phage to a bacterium (and possibly including phage nucleic acid translocation, uptake, into a bacterium's cytoplasm as well).

Discussion

<p>Note that the process of adsorption can be divided into movement, encounter, attachment, and irreversible attachment steps.

Typically diffusion will occur that is followed by random encounter between a phage and a potential bacterial host. If phage adsorption proteins possess sufficient affinity for phage receptors found on the host surface (adsorption affinity), then at least reversible attachment may occur.

Irreversible attachment involves stronger interactions between the virus particle and the bacterial surface as well as irreversible conformational changes in the virion that are associated with phage genome wikipedia.org/wiki/Translocation" target="_blank" class="bap-term">translocation into the cytoplasm of the bacterial cell.

This is the definition from Adams (1959), p. 439): "Attachment of phage particle to bacterium, Irreversible adsorption">irreversible unless otherwise stated."

External links

References

  • Adams (1959). Bacteriophages. Interscience Publishers, New York.

How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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Adsorption — terms.phage.orgphage.org — Stephen T. Abedon — Version 2026.05.14