๐Ÿ”ฌ Adsorption Affinity

The likelihood of phage irreversible adsorption given collision with a class="bap-term">bacterium.

by Stephen T. Abedon Ph.D. (abedon.1@osu.edu)

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About this entry: Adsorption Affinity is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1

phage.org/terms/adsorption_affinity.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

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Adsorption Affinity: The likelihood of phage irreversible adsorption given collision with a class="bap-term">bacterium.

Discussion

<p>The affinity that a phage has for the surface of a bacterium can by further subdivided into three components: (1) the phage ability to interact with and attach to the phage receptor molecule given collision of that molecule with the appropriate phage adsorption protein, (2) the density of phage receptor molecules found on the surface of a bacterium (since a phage has to collide with a molecule to interact with it/attach to it), and (3) the degree to which the molecule is not hidden such as under extracellular polymeric substances.

For consideration of the evolution of phage adsorption affinity as a phage adaptation, see Chan and Abedon (2012).

External links

References

  • Chan and Abedon (2012).

How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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Adsorption Affinity — terms.phage.orgphage.org — Stephen T. Abedon — Version 2026.05.14