๐Ÿ”ฌ Depressor Effect

Reduction in expected burst size given coinfection by dissimilar phages.

by Stephen T. Abedon Ph.D. (abedon.1@osu.edu)

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About this entry: Depressor Effect is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1

phage.org/terms/depressor_effect.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

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Depressor Effect: Reduction in expected burst size given coinfection by dissimilar phages.

Discussion

<p>The depressor effect can be a concern given the use of high-multiplicity phage-cocktail phage therapy. This may be less of a concern given active treatment (that is, starting with fewer phages) and also should be readily testable prior to in vivo or in situ trials via thorough Phenotype">phenotypic phage as well as cocktail characterization in the wikipedia.org/wiki/Laboratory" class="bap-term" target=_blank>laboratory.

For references as well as additional discussion concerning the depressor effect, see Abedon (1994).

External links

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References

  • Abedon (1994).

How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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Depressor Effect — terms.phage.org — phage.org — Stephen T. Abedon — Version 2026.05.14