🔬 Attachment Site

(1) Locations of site-specific recombination in both phage and bacterial genomes during phage insertion into a bacterium's chromosome, which is associated with temperate phage reduction to a prophage state. (2) The location on the surface of a bacterium that a phage recognizes in the course of adsorption.

by Stephen T. Abedon Ph.D. Steve Abedon, Ph.D., has taught well over 100 individual classes and ~10 individual courses (including introductory biology, microbiology, physiology, biochemistry, etc.) over his 30+ years as a college professor. He has over 150 publications, including multiple monographs, and is ranked in the top 1 or 2 percent among researchers of all disciplines worldwide. His research focuses on bacteriophage biology and phage therapy. (abedon.1@osu.edu)

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About this entry: Attachment Site is one of a growing set of phage biology and phage therapy terms defined here. For more phage terms, see Abedon, S.T. (2025). Phage Therapy Annotated Glossary. Preprints.org. 10.20944/preprints202508.0347.v1
To share a particular section, use the 🔗 link beside its heading, which copies a web address that opens the page right there. To cite this page: Abedon, S.T. (2026). Phage Terms. terms.phage.org.  ·  DOI: 10.5281/zenodo.20173633

phage.org/terms/attachment_site.html  ·  Abedon’s Books  ·  DOI: 10.5281/zenodo.20173633

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Attachment Site: (1) Locations of site-specific recombination in both phage and bacterial genomes during phage insertion into a bacterium's chromosome, which is associated with temperate phage reduction to a prophage state. (2) The location on the surface of a bacterium that a phage recognizes in the course of adsorption.

Discussion

Attachment sites for prophage insertion can be quite specific but absence of a phage's preferred attachment site does not necessarily block phage insertion. In addition, prophages that exist as plasmids do not require attachment sites since insertion into the host chromosome is not required for lysogenization.

In terms of virion attachment to a bacterial surface, this event can be either reversible or irreversible, depending on the phage involved, with the reversible step, of course, preceding the irreversible step.

How to cite this page

Abedon, S.T. (2026). Phage Terms. https://terms.phage.org  ·  10.5281/zenodo.20173633

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