by Stephen T. Abedon Ph.D. Steve Abedon, Ph.D., has taught well over 100 individual classes and ~10 individual courses (including introductory biology, microbiology, physiology, biochemistry, etc.) over his 30+ years as a college professor. He has over 150 publications, including multiple monographs, and is ranked in the top 1 or 2 percent among researchers of all disciplines worldwide. His research focuses on bacteriophage biology and phage therapy. (abedon.1@osu.edu)
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phage.org/terms/preadsorption.html · Abedon’s Books · DOI: 10.5281/zenodo.20173633
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Preadsorption serves as a means of better assuring plaque-size consistency by making sure that the first infections associated with plaque formation are more or less synchronized at the point of plating. Preadsorption also can be used as a means of distinguishing those bacteria which serve as the initial phage host during plaque formation and those bacteria which serve instead as indicator bacteria, i.e., as seen with efficiency of center of infection determinations.
Preadsorption is particularly important to the extent that plaque size serves as a relevant measure, such as a surrogate for phage evolutionary fitness. Preadsorption can also be important when working with phages that display slow rates of adsorption. This is particularly so to the extent that this slow adsorption can impact efficiency of plating, that is, the potential for plaques to become visible to the naked eye over the course of incubation.
Abedon, S.T. (2026). Phage Terms. https://terms.phage.org · 10.5281/zenodo.20173633
Every term in the Glossary of Bacteriophage Terms. The current page is highlighted purple.